Accredited: 1 CEU. Antiretroviral medications effectively control HIV infection, preventing HIV-related morbidity and transmission of the virus to others. Although HIV medications were originally excluded from the BC PharmaNet profile, this changed in May 2020 when the Ministry of Health mandated inclusion of antiretrovirals on PharmaNet to protect patient safety. All pharmacists now have the opportunity to check for antiretroviral drug interactions, but might be unfamiliar with these medications. This presentation provides practical information for pharmacists regarding antiretroviral drug interactions.